Contract Fermentation

With one of the most advanced microbial manufacturing plants in the world, EnviroZyme is proud to offer a comprehensive range of contract fermentation services that cater to the diverse needs of manufacturers across a range of industries. From small- to large-scale runs, we drive innovation and success for our partners through:

  • An extensive in-house collection of high-quality pure cultures
  • Aptitude for proprietary IP-owned microbes, with safeguards in place to protect intellectual property
  • Research and development for inoculum preparation, media formulation, and fermentation process optimization
  • Downstream competencies in centrifugation, spray drying, and packaging
Contract Fermentation

Our Methodology Ensures High Quality

Compliance Leadership

Compliance Leadership

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Biological Integrity

ISO and cGMP are the world’s most important benchmarks for quality, so you can be assured of pure, live, and sufficient bacteria concentrations for your products’ core functionality.

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Animal Feed Additives

We have implemented identification and effective prevention of potential hazards for the probiotics we make and strictly adhere to FDA guidelines for their fermentation, package, and shipment.

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Continuous Inspection

These are not one-time designations. Internal and external audits are conducted regularly to ensure compliance and guarantee that we’ll continue to deliver top-quality and outstanding service.

Stringent Quality Control System

Stringent Quality Control System

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Empirical Workflow

We test multiple agar types, media, and incubation conditions for optimal growth and perform extensive validation before, during, and after fermentation.

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Expanded Test Panel

Every step of the way, we conduct microscopic checks, purity platings, optical density readings, growth monitoring, and count verifications.

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Our Promise

We guarantee our high-yield strains and blends to be contamination-free and with the correct bacteria count—always striving for zero defects the first time.

Capabilities & Partnership Process

Project Consultation

Project Consultation

After a nondisclosure agreement (NDA) has been completed, we welcome partners to visit our state-of-the-art facility. In addition to touring, we'll discuss the project requirements in relation to our equipment and technical capabilities to grow, scale, and support. A variety of our experts are available for consultation, including:

  • Degreed fermentation techs in biology/engineering​
  • Chemical Engineers​
  • Microbiologists​
  • Biologists​
  • Research and development team​
  • Quality control team​
  • Regulatory team​
  • Marketing team​

Best-In-Class Equipment

Plant, Process & Production Scale

Plant, Process & Production Scale

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Fermenters

  • 1,000-liter seed fermenter (aerobic) ​
  • 4,000- and 30,000-liters main fermenters (aerobic) with high ​oxygen transfer rate​
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Controls

  • Three 660-liter additional vessels for ​pH and foam control​
  • One custom designed HMI ​Control System​
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Post-Harvest

  • Spray dryer ​(250kg/h evaporation rate)​
  • Centrifuge (2.2m3/h-7,000 rpm)
Full Technical Lab

Full Technical Lab

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Development

  • Benchtop fermenters
  • Autoclaves​
  • Incubators/incubator shakers
  • Bioreactor
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Testing

  • HPLC (High Pressure Liquid Chromatography)​
  • Phase contrast microscopy​
  • pH meter​
  • Homogenizer​-Mixer
  • Biosafety cabinet
  • Laminar air flow hood
  • Spectrophotometers
  • Viscometer
  • Gang-stirrer (dissolution testing)
  • Refrigerated centrifuge​
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Preservation

  • Lab scale freeze drier​
  • Cryofreezer​

Popular Strains Most Used Across Applications

Bacillus subtilis

Bacillus subtilis

Bacillus amyloliquefaciens

Bacillus amyloliquefaciens

Bacillus licheniformis

Bacillus licheniformis

Bacillus megaterium

Bacillus megaterium

Bacillus pumilus

Bacillus pumilus

Bacillus velezensis

Bacillus velezensis

Paenibacillus polymyxa

Paenibacillus polymyxa

Brevibacillus laterosporus

Brevibacillus laterosporus

Contact Us

We have available capacity to contract ferment the right microbial strains for your business. Contact us to jumpstart the supplier vetting process and learn how our capabilities set a new standard for consistency and quality with:

  • FDA registration for probiotic fermentation
  • ISO 9001:2015 certification
  • Current Good Manufacturing Practices (cGMP) compliance
  • Robust quality management processes

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Looking for a More Turnkey Solution?

EnviroZyme has the ability to contract manufacture product solutions for service providers, distributors, retail buyers, or manufacturers seeking to reliably simplify and consolidate their offering.

  • Existing high-performing formulations and packaging solutions
  • Leverage our economies of scale and consolidated supply chain
  • Full brand support, from packaging graphics to collateral

Manufacturing Capabilities

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